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Home - Products - Metabolic Enzyme/Protease - Fatty Acid Synthase - FT113

FT113

CAS No. 1630808-89-7

FT113( —— )

Catalog No. M21632 CAS No. 1630808-89-7

FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 33 In Stock
5MG 29 In Stock
10MG 50 In Stock
25MG 113 In Stock
50MG 194 In Stock
100MG 333 In Stock
200MG 462 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FT113
  • Note
    Research use only, not for human use.
  • Brief Description
    FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.
  • Description
    FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Athymic nude mice bearing MV-411 cellsDosage:5, 25, or 50 mg/kg Administration:P.O., twice daily for 16 daysResult:Caused 32 % and 50% tumor growth inhibition at 25 and 50 mg/kg, respectively in mice.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Fatty Acid Synthase
  • Recptor
    FAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1630808-89-7
  • Formula Weight
    409.41
  • Molecular Formula
    C22H20FN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL (152.66 mM; Need ultrasonic)
  • SMILES
    OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Martin MW et al. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006.
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