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Pamoic acid

CAS No. 130-85-8

Pamoic acid( —— )

Catalog No. M21619 CAS No. 130-85-8

Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 Get Quote
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Biological Information

  • Product Name
    Pamoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
  • Description
    Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR35
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    130-85-8
  • Formula Weight
    388.37
  • Molecular Formula
    C23H16O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (128.74 mM)
  • SMILES
    OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
  • Chemical Name
    44'-Methylenebis(3-hydroxy-2-naphthoic acid)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhao P Sharir H Kapur A et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology 2010 78(4):560-568.
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