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1-Cyclohexyl-3-dodecyl urea

CAS No. 402939-18-8

1-Cyclohexyl-3-dodecyl urea( CDU | N-Cyclohexyl-N-dodecyl urea | NCND )

Catalog No. M21583 CAS No. 402939-18-8

1-Cyclohexyl-3-dodecyl urea is a highly selective soluble epoxide hydrolase (sEH) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    1-Cyclohexyl-3-dodecyl urea
  • Note
    Research use only, not for human use.
  • Brief Description
    1-Cyclohexyl-3-dodecyl urea is a highly selective soluble epoxide hydrolase (sEH) inhibitor.
  • Description
    1-Cyclohexyl-3-dodecyl urea is a highly selective soluble epoxide hydrolase (sEH) inhibitor.
  • In Vitro
    ——
  • In Vivo
    1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) (?intraperitoneal injection; 3mg/day; 4 days) lowers systolic blood pressure by 30 mm Hg in Ang II hypertensive animals, whereas the corn oil vehicle has no effect on blood pressure in normotensive or Ang II hypertensive animals. Animal Model:Male Sprague-Dawley ratsDosage:3mg/day Administration:Intraperitoneal injection; 4 days Result:Had antihypertensive properties.
  • Synonyms
    CDU | N-Cyclohexyl-N-dodecyl urea | NCND
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    sEH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    402939-18-8
  • Formula Weight
    310.52
  • Molecular Formula
    C19H38N2O
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol:16.67 mg/mL (53.68 mM; Need ultrasonic)
  • SMILES
    CCCCCCCCCCCCNC(=O)NC1CCCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Imig JDet al. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.Hypertension. 2002 Feb;39(2 Pt 2):690-4.
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