Erythrodiol
CAS No. 545-48-2
Erythrodiol( —— )
Catalog No. M21516 CAS No. 545-48-2
Erythrodiol an olive oil component promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 69 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 276 | In Stock |
|
| 100MG | 421 | In Stock |
|
| 200MG | 607 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameErythrodiol
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NoteResearch use only, not for human use.
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Brief DescriptionErythrodiol an olive oil component promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
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DescriptionErythrodiol an olive oil component promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
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In VitroErythrodiol (1-15 μM; 24 hours) enhances ABCA1 protein level in a concentration-dependent manner, and reachs significance at 10 and 15 μM. Western Blot Analysis Cell Line:THP-1 macrophage cells Concentration:1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM Incubation Time:24 hours Result:Increased ABCA1 protein expression.
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetABC
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RecptorABCA1
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Research Area——
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Indication——
Chemical Information
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CAS Number545-48-2
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Formula Weight442.7
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Molecular FormulaC30H50O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20 mg/mL (45.18 mM)
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SMILES[H][C@@]12CC(C)(C)CC[C@]1(CO)CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Isosilybin A
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.
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