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DIDS sodium salt
CAS No. 67483-13-0
DIDS sodium salt( MDL101114ZA )
Catalog No. M24686 CAS No. 67483-13-0
DIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 10MG | 31 | In Stock |
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| 25MG | 48 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDIDS sodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionDIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1.
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DescriptionDIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1.
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In VitroConcentration less than 400 μM DIDS has no evident cytotoxic effect on cell viability Pre-treatment with DIDS at the concentration of 100 and 200 μM result in a prevented effect on ALA-SDT-induced cell death, while dose at 50 μM has no inhibition effect. At the concentration of 400 μM DIDS itself slightly decreases the cell viability, although there is no significant statistic difference as compared with the untreated control. Pre-treatment with DIDS (100 μM) clearly inhibit caspase-3 and caspase-9 activation.
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In Vivo——
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SynonymsMDL101114ZA
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PathwayCell Cycle/DNA Damage
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TargetABC
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RecptorABCA1|VDAC1
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Research Area——
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Indication——
Chemical Information
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CAS Number67483-13-0
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Formula Weight498.48
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Molecular FormulaC16H8N2Na2O6S4
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (100.30 mM; Need ultrasonic)
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SMILESC1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])/C=C/C2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tsou CY, et al. Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis. Acta Physiol (Oxf). 2014 Apr;210(4):799-810.
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