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VPS34 inhibitor 1 (Compound 19 PIK-III analogue)

CAS No. 1383716-46-8

VPS34 inhibitor 1 (Compound 19 PIK-III analogue)( PIK-III analogue )

Catalog No. M21136 CAS No. 1383716-46-8

VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue)
  • Note
    Research use only, not for human use.
  • Brief Description
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
  • Description
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PIK-III analogue
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    Vps34
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1383716-46-8
  • Formula Weight
    391.47
  • Molecular Formula
    C21H25N7O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:78 mg/mL (199.25 mM)
  • SMILES
    CC(C)(O)CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Honda A Harrington E Cornella-Taracido I et al. Potent Selective and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo[J]. ACS Medicinal Chemistry Letters 2015 7(1).
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