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Tasosartan
CAS No. 145733-36-4
Tasosartan( WAY-ANA 756 )
Catalog No. M21071 CAS No. 145733-36-4
Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 126 | In Stock |
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| 2MG | 70 | In Stock |
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| 5MG | 116 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 316 | In Stock |
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| 50MG | 462 | In Stock |
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| 100MG | 644 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTasosartan
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NoteResearch use only, not for human use.
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Brief DescriptionTasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
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DescriptionTasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
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In VitroTasosartan is an orally active nonpeptide AngII antagonist that has demonstrates specific and selective AT1 receptor antagonistic activity in vitro.IC50 for inhibition of specific binding of 125I-AngII to rat adrenal membrane in the absence of proteins in binding buffer is 1.2±0.6 nM.
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In VivoAdministration of Tasosartan at doses of 1.0 and 3.0 mg/kg (iv) significantly (p<0.05) attenuates the pressor response to angiotensin-II in rats.
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SynonymsWAY-ANA 756
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PathwayEndocrinology/Hormones
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TargetRAAS
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RecptorAT2 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number145733-36-4
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Formula Weight411.46
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Molecular FormulaC23H21N7O
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (303.80 mM)
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SMILESCc1nc(C)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CC2
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Chemical Name8-((2'-(1H-tetrazol-5-yl)-[11'-biphenyl]-4-yl)methyl)-24-dimethyl-58-dihydropyrido[23-d]pyrimidin-7(6H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Maillard M P Rossat J Brunner H R et al. Tasosartan enoltasosartan and angiotensin II receptor blockade: The confounding role of protein binding[J]. Journal of Pharmacology & Experimental Therapeutics 2000 295(2):649-654.
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