DC260126( —— )

Catalog No. M20675 CAS No. 346692-04-4

DC260126 is a small-molecule antagonist of FFA1 (GPR40).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	51	In Stock
5MG	48	In Stock
10MG	63	In Stock
25MG	137	In Stock
50MG	211	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DC260126
Note

Research use only, not for human use.
Brief Description

DC260126 is a small-molecule antagonist of FFA1 (GPR40).
Description

DC260126 is a small-molecule antagonist of FFA1 (GPR40) .
In Vitro

DC260126 reduces GTP-loading and ERK1/2 phosphorylation stimulated by linoleic acid in GPR40-CHO cells, suppresses palmitic acid potentiated glucose-stimulated insulin secretion, and negatively regulates GPR40 mRNA expression induced by oleic acid in Min6 cells.
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

GPR
Recptor

GPR40
Research Area

——
Indication

——

Chemical Information

CAS Number

346692-04-4
Formula Weight

307.38
Molecular Formula

C16H18FNO2S
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (325.33 mM)
SMILES

CCCCc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Peng S Ting W Yuren Z et al. DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice[J]. PLoS ONE 2013 8(6):e66744-.

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