Cart
sales@molnova.com
Parbendazole
CAS No. 14255-87-9
Parbendazole( SKF 29044 )
Catalog No. M20537 CAS No. 14255-87-9
Parbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 10MG | 44 | In Stock |
|
| 25MG | 67 | In Stock |
|
| 50MG | 91 | In Stock |
|
| 100MG | 160 | In Stock |
|
| 200MG | 239 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameParbendazole
-
NoteResearch use only, not for human use.
-
Brief DescriptionParbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
-
DescriptionParbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
-
In VitroParbendazole is a tubulin destabilizer, with an EC50 of 530?nM, and can induce DNA damage. Parbendazole (2-10 μM) inhibits the assembly of microtubules dose-dependently, with an IC50 of 3 μM. Parbendazole (2-20 μM)-treated cells show an complete absence of microtubules in Vero cells. Parbendazole (up to 10 μM) inhibits the growth of CLd-AXE myxamoebae. Parbendazole (2-5 μM) potently inhibits tubulin purified from the wild-type myxamoebae.
-
In Vivo——
-
SynonymsSKF 29044
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMicrotubule/Tubulin
-
Recptormicrotubule
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number14255-87-9
-
Formula Weight247.29
-
Molecular FormulaC13H17N3O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:4 mg/mL (16.18 mM)
-
SMILESCCCCc1ccc2nc(NC(=O)OC)[nH]c2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lo Y C Senese S France B et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential[J]. Scientific Reports 2017 7(1):11261.
molnova catalog
related products
-
Briciclib
Briciclib is a small molecule that suppresses cyclin D1 accumulation in Y cells.
-
4|-Demethylepipodoph...
A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
-
NQTrp
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
