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Parbendazole
CAS No. 14255-87-9
Parbendazole( SKF 29044 )
Catalog No. M20537 CAS No. 14255-87-9
Parbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | In Stock |
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| 25MG | 64 | In Stock |
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| 50MG | 88 | In Stock |
|
| 100MG | 155 | In Stock |
|
| 200MG | 231 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameParbendazole
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NoteResearch use only, not for human use.
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Brief DescriptionParbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
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DescriptionParbendazole is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.
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In VitroParbendazole is a tubulin destabilizer, with an EC50 of 530?nM, and can induce DNA damage. Parbendazole (2-10 μM) inhibits the assembly of microtubules dose-dependently, with an IC50 of 3 μM. Parbendazole (2-20 μM)-treated cells show an complete absence of microtubules in Vero cells. Parbendazole (up to 10 μM) inhibits the growth of CLd-AXE myxamoebae. Parbendazole (2-5 μM) potently inhibits tubulin purified from the wild-type myxamoebae.
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In Vivo——
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SynonymsSKF 29044
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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Recptormicrotubule
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Research Area——
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Indication——
Chemical Information
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CAS Number14255-87-9
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Formula Weight247.29
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Molecular FormulaC13H17N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:4 mg/mL (16.18 mM)
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SMILESCCCCc1ccc2nc(NC(=O)OC)[nH]c2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lo Y C Senese S France B et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential[J]. Scientific Reports 2017 7(1):11261.
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