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44'-DIMETHOXYBENZIL
CAS No. 1226-42-2
44'-DIMETHOXYBENZIL( p-Anisil )
Catalog No. M20521 CAS No. 1226-42-2
44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | 49 | In Stock |
|
Biological Information
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Product Name44'-DIMETHOXYBENZIL
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NoteResearch use only, not for human use.
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Brief Description44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
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Description44'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
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In VitroBy reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed.
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In Vivo——
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Synonymsp-Anisil
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PathwayOthers
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TargetOther Targets
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RecptorhiCE
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Research Area——
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Indication——
Chemical Information
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CAS Number1226-42-2
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Formula Weight270.28
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Molecular FormulaC16H14O4
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (184.99 mM)
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SMILESCOc1ccc(cc1)C(=O)C(=O)c1ccc(OC)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Guodong Z Hu G E Qiong G U et al. Predicting hiCE inhibitors based upon pharmacophore models derived from the receptor and its ligands[J]. Science China(Chemistry) 2013(10):80-90.
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