Sodium metatungstate

CAS No. 12141-67-2

Sodium metatungstate( Sodium polyoxotungstate | POM-1 )

Catalog No. M23382 CAS No. 12141-67-2

Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
25MG 41 In Stock
50MG 58 In Stock
100MG 84 In Stock
200MG Get Quote In Stock
500MG 209 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Sodium metatungstate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Multiple myeloma (MM) mice developed by 3 weeks of injection of 5t33MM cells Dosage:5 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Had significantly lower spleen weights, fewer tumor cells in the spleen as well as significantly lower monoclonal immunoglobulin component level in circulation.
  • Synonyms
    Sodium polyoxotungstate | POM-1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    12141-67-2
  • Formula Weight
    2869.03
  • Molecular Formula
    H2Na6O40W12
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 48 mg/mL (16.07 mM; Need ultrasonic); DMSO: 48 mg/mL (16.07 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7.
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