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Sodium metatungstate

CAS No. 12141-67-2

Sodium metatungstate( Sodium polyoxotungstate | POM-1 )

Catalog No. M23382 CAS No. 12141-67-2

Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
25MG 41 In Stock
50MG 58 In Stock
100MG 84 In Stock
200MG Get Quote In Stock
500MG 209 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Sodium metatungstate
  • Note
    Research use only, not for human use.
  • Brief Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • Description
    Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Multiple myeloma (MM) mice developed by 3 weeks of injection of 5t33MM cells Dosage:5 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Had significantly lower spleen weights, fewer tumor cells in the spleen as well as significantly lower monoclonal immunoglobulin component level in circulation.
  • Synonyms
    Sodium polyoxotungstate | POM-1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    12141-67-2
  • Formula Weight
    2869.03
  • Molecular Formula
    H2Na6O40W12
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 48 mg/mL (16.07 mM; Need ultrasonic); DMSO: 48 mg/mL (16.07 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7.
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