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MOSLOFLAVONE
CAS No. 740-33-0
MOSLOFLAVONE( —— )
Catalog No. M20486 CAS No. 740-33-0
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
|
| 25MG | 101 | In Stock |
|
| 50MG | 144 | In Stock |
|
| 100MG | 212 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMOSLOFLAVONE
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NoteResearch use only, not for human use.
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Brief DescriptionMOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.
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DescriptionMOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.
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In VitroMosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetTNF
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RecptorTNF-α|IL-1β
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Research Area——
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Indication——
Chemical Information
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CAS Number740-33-0
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Formula Weight298.29
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Molecular FormulaC17H14O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (167.62 mM)
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SMILESCOc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Singh B Sidiq T Joshi P et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.[J]. Natural Product Research 2013 27(23):2227-2230.
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