MOSLOFLAVONE

CAS No. 740-33-0

MOSLOFLAVONE( —— )

Catalog No. M20486 CAS No. 740-33-0

MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 38 In Stock
10MG 61 In Stock
25MG 101 In Stock
50MG 144 In Stock
100MG 212 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MOSLOFLAVONE
  • Note
    Research use only, not for human use.
  • Brief Description
    MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.
  • Description
    MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM respectively.
  • In Vitro
    Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α|IL-1β
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    740-33-0
  • Formula Weight
    298.29
  • Molecular Formula
    C17H14O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (167.62 mM)
  • SMILES
    COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Singh B Sidiq T Joshi P et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.[J]. Natural Product Research 2013 27(23):2227-2230.
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