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5-DEMETHYLNOBILETIN

CAS No. 2174-59-6

5-DEMETHYLNOBILETIN( 5-O-Demethylnobiletin )

Catalog No. M20414 CAS No. 2174-59-6

5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	116	In Stock
10MG	197	In Stock
25MG	345	In Stock
50MG	482	In Stock
100MG	716	In Stock
500MG	1557	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

5-DEMETHYLNOBILETIN
Note

Research use only, not for human use.
Brief Description

5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
Description

5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
In Vitro

5-O-Demethylnobiletin (5-demethylnobiletin) promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent signaling pathways.
In Vivo

——
Synonyms

5-O-Demethylnobiletin
Pathway

Immunology/Inflammation
Target

Lipoxygenase
Recptor

LOX
Research Area

——
Indication

——

Chemical Information

CAS Number

2174-59-6
Formula Weight

388.37
Molecular Formula

C20H20O8
Purity

>98% (HPLC)
Solubility

DMSO:32 mg/mL (82.39 mM)
SMILES

COc1ccc(cc1OC)-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1
Chemical Name

2-(34-Dimethoxyphenyl)-5-hydroxy-678-trimethoxychromen-4-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells.

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