Cart
sales@molnova.com
Home - Products - Immunology/Inflammation - Lipoxygenase - 5-DEMETHYLNOBILETIN

5-DEMETHYLNOBILETIN

CAS No. 2174-59-6

5-DEMETHYLNOBILETIN( 5-O-Demethylnobiletin )

Catalog No. M20414 CAS No. 2174-59-6

5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 123 In Stock
10MG 208 In Stock
25MG 364 In Stock
50MG 498 In Stock
100MG 739 In Stock
200MG Get Quote In Stock
500MG 1609 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    5-DEMETHYLNOBILETIN
  • Note
    Research use only, not for human use.
  • Brief Description
    5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
  • Description
    5-DEMETHYLNOBILETIN is a natual product has anti-inflammatory activity it may act through a direct inhibition of 5-LOX without affecting the expression of COX-2.
  • In Vitro
    5-O-Demethylnobiletin (5-demethylnobiletin) promotes neuritogenesis through the activation of MAPK/ERK-, PKC-, and PKA-dependent signaling pathways.
  • In Vivo
    ——
  • Synonyms
    5-O-Demethylnobiletin
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    LOX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2174-59-6
  • Formula Weight
    388.37
  • Molecular Formula
    C20H20O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:32 mg/mL (82.39 mM)
  • SMILES
    COc1ccc(cc1OC)-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1
  • Chemical Name
    2-(34-Dimethoxyphenyl)-5-hydroxy-678-trimethoxychromen-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Neurotrophic action of 5-hydroxylated polymethoxyflavones: 5-demethylnobiletin and gardenin A stimulate neuritogenesis in PC12 cells.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • EUK 134

    EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.

  • Polygalacic acid

    Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity.

  • 4'5-Dihydroxyflavone

    4'5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).

Sign In Join Free