Alisol B( —— )

Catalog No. M20406 CAS No. 18649-93-9

Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	188	In Stock
5MG	187	In Stock
10MG	278	In Stock
25MG	472	In Stock
50MG	644	In Stock
100MG	913	In Stock
200MG	1228	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Alisol B
Note

Research use only, not for human use.
Brief Description

Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions.
Description

Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-Fos which are key transcription factors for osteoclastogenesis.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

RANKL
Research Area

——
Indication

——

Chemical Information

CAS Number

18649-93-9
Formula Weight

472.7
Molecular Formula

C30H48O4
Purity

>98% (HPLC)
Solubility

DMSO:95 mg/mL (200.97 mM)
SMILES

[H][C@@]1(OC1(C)C)[C@@H](O)C[C@@H](C)C1=C2C[C@H](O)[C@@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@]3(C)[C@@]2(C)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lee J W Kobayashi Y Nakamichi Y et al. Alisol-B a novel phyto-steroid suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice[J]. Biochemical Pharmacology 2010 80(3):352-361.

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