SAR125884 hydrochlorid

CAS No. ——

SAR125884 hydrochlorid ( —— )

Catalog No. M20372 CAS No. ——

SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile(IC50=4.2 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 101 Get Quote
10MG 168 Get Quote
25MG 361 Get Quote
50MG 687 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    SAR125884 hydrochlorid
  • Note
    Research use only, not for human use.
  • Brief Description
    SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile(IC50=4.2 nM).
  • Description
    SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile(IC50=4.2 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    c-Met/HGFR
  • Recptor
    MET RTK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    550.6
  • Molecular Formula
    C25H23FN8O2S2?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.Fc1ccc(cc1)-c1ccc2nnc(Sc3ccc4nc(NC(=O)NCCN5CCOCC5)sc4c3)n2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.The Selective Intravenous Inhibitor of the MET Tyrosine Kinase SAR125844 Inhibits Tumor Growth in MET-Amplified Cancer[J]. Molecular Cancer Therapeutics 2015 14(2):384-394.
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