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GSK963 (Racemate)
CAS No. 2049868-46-2
GSK963 (Racemate)( —— )
Catalog No. M20223 CAS No. 2049868-46-2
GSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
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| 2MG | 41 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 116 | In Stock |
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| 25MG | 235 | In Stock |
|
| 50MG | 369 | In Stock |
|
| 100MG | 541 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK963 (Racemate)
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NoteResearch use only, not for human use.
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Brief DescriptionGSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
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DescriptionGSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
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In Vitro——
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In VivoAnimal Model:C57BL/6 mice.Dosage:0.2 mg/kg, 2 mg/kg, 10?mg/kg.Administration:IP once.Result:Protected mice from TNF+zVAD-induced hypothermia.
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Synonyms——
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PathwayApoptosis
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TargetTNF
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RecptorRIP1
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Research Area——
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Indication——
Chemical Information
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CAS Number2049868-46-2
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Formula Weight230.31
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Molecular FormulaC14H18N2O?
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Purity>98% (HPLC)
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SolubilityDMSO:40 mg/mL (173.67 mM)
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SMILESCC(C)(C)C(=O)N1N=CCC1c1ccccc1
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Chemical Name22-Dimethyl-1-(5(S)-phenyl-45-dihydro-pyrazol-1-yl)-propan-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Berger SB et al. Characterization of GSK'963: a structurally distinct potent and selective inhibitor of RIP1 kinase. Cell Death Discov. 2015 Jul 27;1:15009.
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