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BI-4464
CAS No. 1227948-02-8
BI-4464( —— )
Catalog No. M20216 CAS No. 1227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 77 | In Stock |
|
| 5MG | 132 | In Stock |
|
| 10MG | 215 | In Stock |
|
| 25MG | 356 | In Stock |
|
| 50MG | 530 | In Stock |
|
| 100MG | 772 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI-4464
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NoteResearch use only, not for human use.
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Brief DescriptionBI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
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DescriptionBI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetFAK
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RecptorPTK2/FAK
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Research Area——
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Indication——
Chemical Information
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CAS Number1227948-02-8
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Formula Weight555.56
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Molecular FormulaC28H28F3N5O4
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Purity>98% (HPLC)
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SolubilityDMSO:16.67 mg/mL?(30.01 mM)
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SMILESCOc1cc(ccc1Nc1ncc(c(Oc2cccc3CCC(=O)c23)n1)C(F)(F)F)C(=O)NC1CCN(C)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Popow J et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
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