FAK-IN-10( —— )

Catalog No. M37079 CAS No. 491839-65-7

FAK-IN-10 is an inhibitor of FAK (IC50: 76.3 μM) and demonstrates antitumor activity in MCF-7 and A431 cell lines with IC50 values of 4.23 μM and 0.78 μM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

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Biological Information

Product Name

FAK-IN-10
Note

Research use only, not for human use.
Brief Description

FAK-IN-10 is an inhibitor of FAK (IC50: 76.3 μM) and demonstrates antitumor activity in MCF-7 and A431 cell lines with IC50 values of 4.23 μM and 0.78 μM, respectively.
Description

FAK-IN-10 is an inhibitor of FAK with an IC50 of 76.3 μM. FAK-IN-10 exhibits antitumor activity against MCF-7 and A431 cell lines with IC50s of 4.23 and 0.78 μM,respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

FAK
Recptor

FAK
Research Area

——
Indication

——

Chemical Information

CAS Number

491839-65-7
Formula Weight

376.23
Molecular Formula

C15H10BrN3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (53.16 mM; Ultrasonic (<60°C)
SMILES

O=C(C1=CC=C(Br)C=C1)CSC2=NN=C(O2)C=3C=CN=CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zhang LR, et al. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20(11):3615-21.?

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