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Home - Products - Chromatin/Epigenetic - Histone Demethylase - YF-2

YF-2

CAS No. 1311423-89-8

YF-2( YF 2 )

Catalog No. M20208 CAS No. 1311423-89-8

YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 126 In Stock
5MG 116 In Stock
10MG 187 In Stock
25MG 392 In Stock
50MG 575 In Stock
100MG 817 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    YF-2
  • Note
    Research use only, not for human use.
  • Brief Description
    YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.
  • Description
    YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    YF 2
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    CBP|PCAF|GCN5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1311423-89-8
  • Formula Weight
    430.85
  • Molecular Formula
    C20H22ClF3N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (290.12 mM);Water:Insoluble
  • SMILES
    CCOc1cccc(OCCN(C)C)c1C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.FENG Yen et al. HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF. WO 2011072243A1.
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