Ginkgolide J

CAS No. 107438-79-9

Ginkgolide J( 7-beta-Hydroxyginkgolide A | BN 52024 )

Catalog No. M20162 CAS No. 107438-79-9

Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 155 In Stock
5MG 125 In Stock
10MG 185 In Stock
25MG 313 In Stock
50MG 440 In Stock
100MG 603 In Stock
200MG 812 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Ginkgolide J
  • Note
    Research use only, not for human use.
  • Brief Description
    Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.
  • Description
    Ginkgolide J has neuroprotective activity it can prevent A beta(1-42) induced inhibition of long-term potentiation in the CA1 region of mouse hippocampal slices.
  • In Vitro
    ——
  • In Vivo
    Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons.
  • Synonyms
    7-beta-Hydroxyginkgolide A | BN 52024
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    107438-79-9
  • Formula Weight
    424.4
  • Molecular Formula
    C20H24O10
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    C[C@@H]1C(=O)O[C@H]2C[C@]34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)[C@H](O)[C@]43[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O
  • Chemical Name
    7-beta-Hydroxyginkgolide A

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vitolo O Gong B Cao Z et al. Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide J[J]. Neurobiology of Aging 2009 30(2):257-265.
molnova catalog
related products
  • NSP-805

    NSP-805 is a potent and selective guinea pig cardiac phosphodiesterase 3 (PDE3) inhibitor.

  • MBCQ

    MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.

  • Difamilast

    Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).?