YM976( —— )

Catalog No. M21141 CAS No. 191219-80-4

YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

YM976
Note

Research use only, not for human use.
Brief Description

YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM).
Description

YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

PDE
Recptor

PDE4
Research Area

——
Indication

——

Chemical Information

CAS Number

191219-80-4
Formula Weight

313.78
Molecular Formula

C17H16ClN3O
Purity

>98% (HPLC)
Solubility

——
SMILES

CCc1ccc2c(-c3cccc(Cl)c3)nc(=O)n(CC)c2n1
Chemical Name

4-(3-chlorophenyl)-17-diethyl-1H2H-pyrido[23-d]pyrimidin-2-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Aoki M Kobayashi M Ishikawa J et al. A Novel Phosphodiesterase Type 4 Inhibitor YM976 (4-(3-Chlorophenyl)-17-diethylpyrido[23-d]pyrimidin-2(1H)-one) with Little Emetogenic Activity[J]. Journal of Pharmacology & Experimental Therapeutics 2000 295(1):255-260.

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