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BAI1
CAS No. 335165-68-9
BAI1( —— )
Catalog No. M20096 CAS No. 335165-68-9
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 188 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | 443 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBAI1
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NoteResearch use only, not for human use.
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Brief DescriptionBAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
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DescriptionBAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
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In VitroApoptosis Analysis Cell Line:Mouse MEF Concentration:0.3125 μM , 0.625 μM, 1 μM, 1.25 μM, 1.5 μM, 2.5 μM , 3 μM, 4 μM, 5 4 μM, 10 4 μM Incubation Time:8 hours Result:Inhibited cell death in BAX-dependent manner.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBax
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Research Area——
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Indication——
Chemical Information
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CAS Number335165-68-9
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Formula Weight467.2
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Molecular FormulaC19H21Br2N3O
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Purity>98% (HPLC)
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SolubilityDMSO: 15 mg/mL (32.1 mM);Water: Insoluble
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SMILESOC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bombrun A et al. 36-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J Med Chem. 2003 Oct 9;46(21):4365-8.
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