Cart
sales@molnova.com
BAI1
CAS No. 335165-68-9
BAI1( —— )
Catalog No. M20096 CAS No. 335165-68-9
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
|
| 5MG | 76 | In Stock |
|
| 10MG | 107 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | 443 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBAI1
-
NoteResearch use only, not for human use.
-
Brief DescriptionBAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
-
DescriptionBAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
-
In VitroApoptosis Analysis Cell Line:Mouse MEF Concentration:0.3125 μM , 0.625 μM, 1 μM, 1.25 μM, 1.5 μM, 2.5 μM , 3 μM, 4 μM, 5 4 μM, 10 4 μM Incubation Time:8 hours Result:Inhibited cell death in BAX-dependent manner.
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetBcl-2
-
RecptorBax
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number335165-68-9
-
Formula Weight467.2
-
Molecular FormulaC19H21Br2N3O
-
Purity>98% (HPLC)
-
SolubilityDMSO: 15 mg/mL (32.1 mM);Water: Insoluble
-
SMILESOC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Bombrun A et al. 36-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. J Med Chem. 2003 Oct 9;46(21):4365-8.
molnova catalog
related products
-
S44563
S44563 is a potent, dual Bcl-2/Bcl-XL inhibitor with IC50 of 131 and 140 nM, respectively.
-
Isoverticine
Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.
-
BCL6-IN-3
BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity.
