Cefcapene Pivoxil Hydrochloride

Research use only, not for human use.

Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity.

Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil the ester bond is cleaved releasing active cefcapene.(In Vivo):Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration.

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Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration. Animal Model:Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×109 CFU)Dosage:100 mg/kg Administration:Oral administration; 100mg/kg; 4 days Result:Was against H. influenzae colonization in mouse lung.

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GPCR/G Protein

Antibacterial

Antibacterial

Inflammation/Immunology

Bacterial infections; Ophthalmic infections; Otorhinolaryngological infections; Respiratory tract infections; Skin and soft tissue infections

147816-24-8

622.12

C23H29N5O8S2

>98% (HPLC)

DMSO: 90 mg/mL

O.Cl.CC\C=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)c1csc(N)n1

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(-20℃)

With Ice Pack

≥ 2 years