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7-Dehydrocholesterol
CAS No. 434-16-2
7-Dehydrocholesterol( 7-DHC | Provitamin D3 )
Catalog No. M19772 CAS No. 434-16-2
7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 50MG | 31 | In Stock |
|
| 100MG | 44 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 104 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name7-Dehydrocholesterol
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NoteResearch use only, not for human use.
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Brief Description7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
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Description7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.(In Vitro):7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen.
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In Vitro7-Dehydrocholesterol is a biosynthetic precursor of cholesterol and vitamin D3. 7-Dehydrocholesterol is present in relatively high concentration in skin where it is converted to pre-vitamin D3 upon UV irradiation and where it is also exposed to exogenous radical sources and oxygen.
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In Vivo——
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Synonyms7-DHC | Provitamin D3
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number434-16-2
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Formula Weight384.64
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Molecular FormulaC27H44O
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Purity>98% (HPLC)
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SolubilityDMSO:10mM
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SMILESCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lehmann B Genehr T Knuschke P et al. UVB-Induced Conversion of 7-Dehydrocholesterol to 1α25-Dihydroxyvitamin D3 in an In Vitro Human Skin Equivalent Model[J]. Journal of Investigative Dermatology 2001 117(5):1179.
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