UDP disodium salt( Uridine 5'-diphosphate disodium salt hyd )

Catalog No. M19585 CAS No. 27821-45-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

UDP disodium salt
Note

Research use only, not for human use.
Brief Description

UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.
Description

UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6) stimulating the production of inflammatory mediators phagocytosis and vasoconstriction. UDP also acts as an antagonist of P2Y14.
In Vitro

RT-PCRCell Line:Primary microglia Concentration:100 μM Incubation Time:For 15 min Result:Significantly induced microglial CCL2 and CCL3 mRNA expression.
In Vivo

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Synonyms

Uridine 5'-diphosphate disodium salt hyd
Pathway

Neuroscience
Target

P2 Receptor
Recptor

P2Y6| P2Y14
Research Area

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Indication

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CAS Number

27821-45-0
Formula Weight

466.14
Molecular Formula

C9H14N2Na2O13P2
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)n1ccc(=O)[nH]c1=O
Chemical Name

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1.Jacobson K.A. et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 5(1) 75-89 (2009).

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