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Diclone

CAS No. 117-80-6

Diclone( Phygon | 23-Dichloro-14-naphthoquinone | Sanquinon )

Catalog No. M19469 CAS No. 117-80-6

2 3- Dichloro- 1 4- naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 88 In Stock
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Biological Information

  • Product Name
    Diclone
  • Note
    Research use only, not for human use.
  • Brief Description
    2 3- Dichloro- 1 4- naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.
  • Description
    2 3- Dichloro- 1 4- naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Phygon | 23-Dichloro-14-naphthoquinone | Sanquinon
  • Pathway
    PROTACs
  • Target
    E3 Ligase Ligand
  • Recptor
    Itch
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    117-80-6
  • Formula Weight
    227.04
  • Molecular Formula
    C10H4Cl2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    ClC1=C(Cl)C(=O)c2ccccc2C1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu Y M et al. 14-Naphthoquinones as inhibitors of Itch a HECT domain-E3 ligase and tumor growth suppressors in multiple myeloma.[J]. European Journal of Medicinal Chemistry 2017 140:84.
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