Z-VAD(OH)-FMK( Z-VAD | Caspase Inhibitor VI )

Catalog No. M19461 CAS No. 161401-82-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Z-VAD(OH)-FMK
Note

Research use only, not for human use.
Brief Description

Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
Description

Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 μM.
In Vitro

Cell Viability Assay Cell Line:HeLa cells Concentration:40 μM Incubation Time:Prtreated for 30 minutes Result:Prevented TSSLT-induced cell death. More than 80% cell survival was observed.
In Vivo

——
Synonyms

Z-VAD | Caspase Inhibitor VI
Pathway

Apoptosis
Target

Caspase
Recptor

Caspase-8
Research Area

——
Indication

——

CAS Number

161401-82-7
Formula Weight

453.46
Molecular Formula

C21H28FN3O7
Purity

>98% (HPLC)
Solubility

DMSO:83 mg/mL (183 mM);Ethanol:83 mg/mL (183 mM);Water:<1 mg/mL
SMILES

CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
Chemical Name

——

1.Garcia-Calvo M et al. J Biol Chem. 1998 273(49) 32608-32613.

Calculator

molnova catalog