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Fmoc-Val-Ala-PAB
CAS No. 1394238-91-5
Fmoc-Val-Ala-PAB( Fmoc-Val-Ala-PAB | ACD linker | Fmoc-Val-Ala-PAB-OH )
Catalog No. M17993 CAS No. 1394238-91-5
Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 33 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameFmoc-Val-Ala-PAB
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NoteResearch use only, not for human use.
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Brief DescriptionFmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
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DescriptionFmoc-Val-Ala-PAB, also known as Fmoc-Val-Ala-PAB-OH, is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In Vivo——
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SynonymsFmoc-Val-Ala-PAB | ACD linker | Fmoc-Val-Ala-PAB-OH
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PathwayApoptosis
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TargetCaspase
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RecptorADCs Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number1394238-91-5
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Formula Weight515.61
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Molecular FormulaC30H33N3O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (64.64 mM)
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SMILESO=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](C(C)C)C(N[C@@H](C)C(NC4=CC=C(CO)C=C4)=O)=O
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Chemical Name(9H-fluoren-9-yl)methyl (S)-1-((S)-1-(4-(hydroxymethyl)phenylamino)-1-oxopropan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dal Corso, A., et al.Synthesis and Biological Evaluation of RGD Peptidomimetic–Paclitaxel Conjugates Bearing Lysosomally Cleavable Linkers，Chem. Eur. J., 21, 6921 (2015).
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