PRX-08066 Maleic acid
CAS No. 866206-55-5
PRX-08066 Maleic acid( PRX-08066 Maleate )
Catalog No. M19194 CAS No. 866206-55-5
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 402 | In Stock |
|
| 5MG | 171 | In Stock |
|
| 10MG | 233 | In Stock |
|
| 25MG | 420 | In Stock |
|
| 50MG | 606 | In Stock |
|
| 100MG | 863 | In Stock |
|
| 200MG | 1172 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePRX-08066 Maleic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionPRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.
-
DescriptionPRX-08066 Maleate is a novel potent and selective 5-HT2B receptor antagonist.
-
In Vitro——
-
In Vivo——
-
SynonymsPRX-08066 Maleate
-
PathwayOthers
-
TargetOther Targets
-
Recptor5-HT2B
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number866206-55-5
-
Formula Weight517.96
-
Molecular FormulaC19H17ClFN5S·C4H4O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N.C(=C\C(=O)O)\C(=O)O
-
Chemical Name5-[[4-[(6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile maleate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
β-CGRP, human
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylalanine amide important for immune recognition, and an a-helix between residues 8 and 18.
-
Methyl isoeugenol
methyl isoeugenol (MIE) is a natural food flavour that constitutes 93.7% of an essential oil from Pimenta pseudocaryophyllus leaf. The leaf extracts of this species are used as a calming agent. As a ubiquitous food additive the application of MIE for treating mood disorders.
-
Picloram
Picloram is an auxinic herbicide that is widely used for controlling broad leaf weeds.
Cart
sales@molnova.com