Glaucocalyxin A

CAS No. 79498-31-0

Glaucocalyxin A( —— )

Catalog No. M19111 CAS No. 79498-31-0

Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 77 In Stock
10MG 123 In Stock
25MG 227 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Glaucocalyxin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery.
  • Description
    Glaucocalyxin A-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expression of X-linked inhibitor of apoptosis protein. Glaucocalyxin A inhibits Akt phosphorylation, suppresses proliferation, and promotes apoptosis in a dose-dependent manner, but not in normal glial cells. Glaucocalyxin A inhibits collagen-stimulated tyrosine phosphorylation of Syk, LAT, and phospholipase Cγ2, the signaling events in collagen receptor GPⅥ pathway. Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand.
  • In Vitro
    Glaucocalyxin A induces apoptosis by mitochondrial apoptotic pathway through several steps including increasing the Bax/Bcl-2 ratio, triggering the intracellular reactive oxygen species (ROS) generation, reducing mitochondrial membrane potential (MMP), and inducing cleavage of caspase-9 and caspase-3.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    Caspase-3|Akt
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    79498-31-0
  • Formula Weight
    332.44
  • Molecular Formula
    C20H28O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (150.41 mM)
  • SMILES
    CC1(C2CC(C34C(C2(CCC1=O)C)CCC(C3O)C(=C)C4=O)O)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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