Dapiprazole Hydrochloride

Research use only, not for human use.

Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.

Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.(In Vivo):Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice.

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Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice. Animal Model:Swiss Albino male CD-1 mice weighing 20 -25 g, acute dependence model Dosage:5, 7.5 and 10 mg/kg (i.p.) or 0.5, 1 and 3 mg/mice (i.c.v.), once Administration:Intraperitoneal injection or intracerebroventricular administration, once Result:Decreased jumping behavior, head shakes and paw shakes when administered just before naloxone.

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Others

Other Targets

α1-adrenergic receptor

Others-Field

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72822-13-0

361.92

C19H28ClN5

>98% (HPLC)

DMSO : ≥ 31 mg/mL; 85.66 mM

Cc1ccccc1N1CCN(CC1)CCc1nnc2n1CCCC2.Cl

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(-20℃)

With Ice Pack

≥ 2 years