Cucurbitacin IIA( —— )

Catalog No. M18849 CAS No. 58546-34-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Cucurbitacin IIA
Note

Research use only, not for human use.
Brief Description

Cucurbitacin IIA can induce apoptosis and enhance autophagy, contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases.
Description

Cucurbitacin IIA can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

TNF
Recptor

Survivin
Research Area

——
Indication

——

CAS Number

58546-34-2
Formula Weight

562.74
Molecular Formula

C32H50O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (44.43 mM)
SMILES

CC(=O)OC(C)(C)CCC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(C4(C)C)O)O)C)C)C)O)O
Chemical Name

——