Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - AChR - Rhapontigenin

Rhapontigenin

CAS No. 500-65-2

Rhapontigenin( —— )

Catalog No. M18663 CAS No. 500-65-2

Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 93 In Stock
10MG 175 In Stock
25MG 339 In Stock
50MG 499 In Stock
100MG 625 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Rhapontigenin
  • Note
    Research use only, not for human use.
  • Brief Description
    Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.
  • Description
    Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).
  • In Vitro
    ——
  • In Vivo
    Animal Model:ICR mice Dosage:25mg/kg Administration:25mg/kg; intraperitoneal injection Result:Showed anti-thrombosis activity with 60% protection.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    CYP1A1
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    500-65-2
  • Formula Weight
    258.3
  • Molecular Formula
    C15H14O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (483.99 mM)
  • SMILES
    COc1c(cc(cc1)/C=C/c1cc(cc(c1)O)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jo SP1, Kim JK2, Lim YH1.Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet.Planta Med. 2014 Aug;80(13):1067-71.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Syn-Ake acetate

    Syn-Ake acetate is a muscarinic acetylcholine receptor antagonist.

  • Encenicline

    Encenicline is a selective α7 nicotinic acetylcholine receptor?(nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.

  • JHU 37160

    JHU 37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively.

Sign In Join Free