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Rhapontigenin
CAS No. 500-65-2
Rhapontigenin( —— )
Catalog No. M18663 CAS No. 500-65-2
Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 88 | In Stock |
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| 10MG | 166 | In Stock |
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| 25MG | 321 | In Stock |
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| 50MG | 483 | In Stock |
|
| 100MG | 605 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRhapontigenin
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NoteResearch use only, not for human use.
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Brief DescriptionRhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.
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DescriptionRhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).
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In Vitro——
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In VivoAnimal Model:ICR mice Dosage:25mg/kg Administration:25mg/kg; intraperitoneal injection Result:Showed anti-thrombosis activity with 60% protection.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorCYP1A1
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number500-65-2
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Formula Weight258.3
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Molecular FormulaC15H14O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (483.99 mM)
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SMILESCOc1c(cc(cc1)/C=C/c1cc(cc(c1)O)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jo SP1, Kim JK2, Lim YH1.Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet.Planta Med. 2014 Aug;80(13):1067-71.
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