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Saccharin 1-methylimidazole (SMI)
CAS No. 482333-74-4
Saccharin 1-methylimidazole (SMI)( Saccharin 1-methylimidazole )
Catalog No. M18618 CAS No. 482333-74-4
SMI is a general-purpose activator used for DNA and RNA synthesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 25MG | 32 | In Stock |
|
| 50MG | 47 | In Stock |
|
| 100MG | 77 | In Stock |
|
| 200MG | 101 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSaccharin 1-methylimidazole (SMI)
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NoteResearch use only, not for human use.
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Brief DescriptionSMI is a general-purpose activator used for DNA and RNA synthesis.
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DescriptionSaccharin 1-methylimidazole is an activator for DNA and RNA synthesis.
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In VitroExposure to certain concentrations of the entirely different promoters phenobarbital and the calcium and sodium salts of saccharin (22, 23, 25, 29, 38) stimulates calcium-deprived T51B cells to initiate DNA synthesis as rapidly and as effectively, or nearly as effectively, as raising the extracellular calcium concentration to 1.25 mM.
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In Vivo——
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SynonymsSaccharin 1-methylimidazole
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA/RNA Synthesis
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number482333-74-4
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Formula Weight265.29
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Molecular FormulaC7H5NO3S·C4H6N2
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Purity>98% (HPLC)
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SolubilityDMSO : 6 mg/mL 22.62 mM
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SMILESO=C1c2c(cccc2)S(=O)(=O)N1.Cn1ccnc1
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Chemical Name1,1-Dioxide-1,2-benzisothiazol-3(2H)-one 1-methyl-1H-imidazole salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Boynton AL, et al. Cancer Res. 1980 Dec;40(12):4541-5.
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