Cart
sales@molnova.com
Saccharin 1-methylimidazole (SMI)
CAS No. 482333-74-4
Saccharin 1-methylimidazole (SMI)( Saccharin 1-methylimidazole )
Catalog No. M18618 CAS No. 482333-74-4
SMI is a general-purpose activator used for DNA and RNA synthesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 25MG | 32 | In Stock |
|
| 50MG | 47 | In Stock |
|
| 100MG | 77 | In Stock |
|
| 200MG | 101 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSaccharin 1-methylimidazole (SMI)
-
NoteResearch use only, not for human use.
-
Brief DescriptionSMI is a general-purpose activator used for DNA and RNA synthesis.
-
DescriptionSaccharin 1-methylimidazole is an activator for DNA and RNA synthesis.
-
In VitroExposure to certain concentrations of the entirely different promoters phenobarbital and the calcium and sodium salts of saccharin (22, 23, 25, 29, 38) stimulates calcium-deprived T51B cells to initiate DNA synthesis as rapidly and as effectively, or nearly as effectively, as raising the extracellular calcium concentration to 1.25 mM.
-
In Vivo——
-
SynonymsSaccharin 1-methylimidazole
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA/RNA Synthesis
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number482333-74-4
-
Formula Weight265.29
-
Molecular FormulaC7H5NO3S·C4H6N2
-
Purity>98% (HPLC)
-
SolubilityDMSO : 6 mg/mL 22.62 mM
-
SMILESO=C1c2c(cccc2)S(=O)(=O)N1.Cn1ccnc1
-
Chemical Name1,1-Dioxide-1,2-benzisothiazol-3(2H)-one 1-methyl-1H-imidazole salt
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Boynton AL, et al. Cancer Res. 1980 Dec;40(12):4541-5.
molnova catalog
related products
-
NITD-2
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation.?
-
Procainamide
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 (DNMT1) inhibitor and a Class 1A antiarrhythmic agent, with potential applications in cancer and arrhythmia research .
-
NCGC00029283
NCGC00029283 is a potent inhibitor of Werner syndrome helicase-nuclease (WRN), displaying inhibitory activity against WRN helicase with an IC 50 value of 2.3 μM.
