Coniferyl aldehyde

Research use only, not for human use.

An isoflavonoid with potential antioxidant activity.

An isoflavonoid with potential antioxidant activity.

Cell Viability Assay Cell Line:Raw264.7 cells inudced with LPS Concentration:0.1 μM, 0.5 μM, 1 μM, 2 μM, 5 μM Incubation Time:Pretreatment with 1 h,and then treated with 24 h Result:Inhibited LPS-induced NO production and cell death.Western Blot Analysis Cell Line:Raw264.7 cells Concentration:0.5 μM, 1 μM, 2 μM, 5 μM Incubation Time:4 h, 8 h, 12 h, 24 h Result:Increased HO-1 protein level in a dose- and time-dependent manner.

Animal Model:B6 male mice (26 g; 8-10 weeks old), surgical-induced osteoarthritis (OA)Dosage:0.05 mmol kg/day (approx. 8.9 mg/kg) Administration:i.p; for 6 weeks Result:Evidently alleviated the medial meniscus cartilage damage in mice subjected to the destabilization.

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Others

Other Targets

Antioxidant

Others-Field

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458-36-6

178.18

C10H10O3

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (561.23 mM)

COC1=C(C=CC(=C1)C=CC=O)O

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(-20℃)

With Ice Pack

≥ 2 years