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K-Ras(G12C) Inhibitor 6

CAS No. 2060530-16-5

K-Ras(G12C) Inhibitor 6( K-Ras(G12C) Inhibitor 6 | MDK30165 )

Catalog No. M17423 CAS No. 2060530-16-5

K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 77 In Stock
5MG 77 In Stock
10MG 139 In Stock
25MG 287 In Stock
50MG 392 In Stock
100MG 548 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    K-Ras(G12C) Inhibitor 6
  • Note
    Research use only, not for human use.
  • Brief Description
    K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
  • Description
    MDK30165, also known as K-Ras(G12C) Inhibitor 6. It has no formal code name. For the convenience of communication, we name it as MDK30165. It has CAS#2060530-16-5, in which the last 5 digit is used for its code name. K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    K-Ras(G12C) Inhibitor 6 | MDK30165
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    K-Ras
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    2060530-16-5
  • Formula Weight
    405.33
  • Molecular Formula
    C17H22Cl2N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Clc1ccc(OCC(=O)N2CCC(NC(=O)CCCS)CC2)c(Cl)c1
  • Chemical Name
    N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8895-900.
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