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Sirtinol
CAS No. 410536-97-9
Sirtinol( Sirtinol )
Catalog No. M18528 CAS No. 410536-97-9
Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
|
| 2MG | 34 | In Stock |
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| 5MG | 50 | In Stock |
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| 10MG | 81 | In Stock |
|
| 25MG | 179 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 498 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1097 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSirtinol
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NoteResearch use only, not for human use.
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Brief DescriptionSirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
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DescriptionSirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle.
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In Vitro——
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In Vivo——
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SynonymsSirtinol
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PathwayOthers
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TargetOther Targets
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RecptorSIRT1| SIRT2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number410536-97-9
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Formula Weight394.47
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Molecular FormulaC26H22N2O2
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Purity>98% (HPLC)
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SolubilityDMSO : 6.5 mg/mL 16.48 mM;
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SMILESCC(c1ccccc1)NC(=O)c1ccccc1/N=C/c1c(O)ccc2ccccc12
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Chemical Name2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.
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