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Sirtinol

CAS No. 410536-97-9

Sirtinol( Sirtinol )

Catalog No. M18528 CAS No. 410536-97-9

Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 50 In Stock
2MG 34 In Stock
5MG 50 In Stock
10MG 81 In Stock
25MG 179 In Stock
50MG 335 In Stock
100MG 498 In Stock
200MG Get Quote In Stock
500MG 1097 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Sirtinol
  • Note
    Research use only, not for human use.
  • Brief Description
    Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
  • Description
    Sirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Sirtinol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SIRT1| SIRT2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    410536-97-9
  • Formula Weight
    394.47
  • Molecular Formula
    C26H22N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 6.5 mg/mL 16.48 mM;
  • SMILES
    CC(c1ccccc1)NC(=O)c1ccccc1/N=C/c1c(O)ccc2ccccc12
  • Chemical Name
    2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.
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