Glycitein

Research use only, not for human use.

Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.

Glycitein is found in soy and red clover. It exhibits a variety of biological activities, including increasing Nrf2-related antioxidative signaling, preventing invasion in glioma cells destabilizing amyloid-β aggregates and preventing fibril assembly, and inhibiting osteoclast generation.

Cell Viability Assay Cell Line:human gastric cancer cells (AGS, MKN-28, MKN-45, NCI-N87, YCC-1, YCC-6, SNU-5, SNU-216, SNU-484, SNU-668)Concentration:24 h Incubation Time:0-100 μM Result:IC50: 30.98, 60.17, 35.07, 36.05, 33.11, 88.62, 97.68, 83.02, 46.87, 87.55 μM respectively.Apoptosis Analysis Cell Line:AGS cells Concentration:30 μM Incubation Time:3, 6, 12, and 24 hr Result:Increased the expression of Bax, Caspase-3 and cleaved PARP protein, and decreased levels of Bcl-2.

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Glycitein | Q-100465

Neuroscience

P2 Receptor

Others

Others-Field

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40957-83-3

284.26

C16H12O5

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (87.95 mM)

COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O

7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one

(-20℃)

With Ice Pack

≥ 2 years