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Glycitein
CAS No. 40957-83-3
Glycitein( Glycitein | Q-100465 )
Catalog No. M18527 CAS No. 40957-83-3
Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 44 | In Stock |
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| 10MG | 60 | In Stock |
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| 25MG | 93 | In Stock |
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| 50MG | 137 | In Stock |
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| 100MG | 200 | In Stock |
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| 200MG | 296 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGlycitein
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NoteResearch use only, not for human use.
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Brief DescriptionGlycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
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DescriptionGlycitein is found in soy and red clover. It exhibits a variety of biological activities, including increasing Nrf2-related antioxidative signaling, preventing invasion in glioma cells destabilizing amyloid-β aggregates and preventing fibril assembly, and inhibiting osteoclast generation.
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In VitroCell Viability Assay Cell Line:human gastric cancer cells (AGS, MKN-28, MKN-45, NCI-N87, YCC-1, YCC-6, SNU-5, SNU-216, SNU-484, SNU-668)Concentration:24 h Incubation Time:0-100 μM Result:IC50: 30.98, 60.17, 35.07, 36.05, 33.11, 88.62, 97.68, 83.02, 46.87, 87.55 μM respectively.Apoptosis Analysis Cell Line:AGS cells Concentration:30 μM Incubation Time:3, 6, 12, and 24 hr Result:Increased the expression of Bax, Caspase-3 and cleaved PARP protein, and decreased levels of Bcl-2.
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In Vivo——
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SynonymsGlycitein | Q-100465
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PathwayNeuroscience
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TargetP2 Receptor
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number40957-83-3
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Formula Weight284.26
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Molecular FormulaC16H12O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (87.95 mM)
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SMILESCOC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O
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Chemical Name7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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