20(R)-Propanaxadiol

Research use only, not for human use.

20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.

R-Ginsenodie Rg3 γ2 GABA-A receptor agonist, 7.1 K+ channel activator, α10 nAChR antagonist found in Panax. It exhibits a wide variety of biological activities, including decreasing expression of pro-inflammatory cytokines, reducing oxidative stress, and inhibiting tubular formation and migration of endothelial progenitor cells.

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Animal Model:Male Kunming mice weighing 18-22 g Dosage:0.05 mg/kg, 0.1 mg/kg, 0.5 mg/kg (5 μL each nostril) Administration:Intranasal administration; for 2 weeks Result:Significantly prolonged the weight-loaded swimming time, and also increased the hepatic glycogen levels.

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Cell Cycle/DNA Damage

DNA/RNA Synthesis

Others

Others-Field

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38243-03-7

785.02

C42H72O13

>98% (HPLC)

In Vitro:?DMSO : 41.67 mg/mL (53.08 mM)

C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2([C@H]([C@@H](C1)O)[C@H](CC2)[C@@](C)(CCC=C(C)C)O)C)C)C)(C)C)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)CO

(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((3R,5S,8R,9R,10R,12S,13R,14R,17S)-12-hydroxy-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

(-20℃)

With Ice Pack

≥ 2 years