Tiaprofenic acid

Research use only, not for human use.

Tiaprofenic acid is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.

Tiaprofenic acid is a non-steroidal anti-inflammatory drug (NSAID) of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain Long-term use of tiaprofenic acid is associated with severe cystitis, roughly 100 times more commonly than other NSAIDs. It is contraindicated in patients with cystitis and urinary tract infections.(In Vivo):Female Lewis rats received either Tiaprofenic acid (as an intravenous (iv.) bolus injection of 15 mg/kg and constant infusion of 0.02 mg/min) for 6 h. Tiaprofenic acid results in a significant decrease in serum sulfate concentrations and increase in sulfate clearance ratio. There is also a significant decrease in the fraction of sulfate reabsorbed by the kidneys.

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Female Lewis rats received either Tiaprofenic acid (as an intravenous (iv.) bolus injection of 15 mg/kg and constant infusion of 0.02 mg/min) for 6 h. Tiaprofenic acid results in a significant decrease in serum sulfate concentrations and increase in sulfate clearance ratio. There is also a significant decrease in the fraction of sulfate reabsorbed by the kidneys.

Tiaprofenic acid

GPCR/G Protein

S1P Receptor

Others

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33005-95-7

260.31

C14H12O3S

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (384.16 mM)

CC(C(O)=O)c1ccc(s1)C(=O)c1ccccc1

2-(5-benzoyl-2-thienyl)propanoic acid

(-20℃)

With Ice Pack

≥ 2 years