Cyclizine hydrochloride

Research use only, not for human use.

Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.

Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.(In Vitro):Cyclizine (100 μM) significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.(In Vivo):Cyclizine (1, 10 mg/kg) enhances locomotor activity of mice in a dose-dependent manner.

Cyclizine (100 μM) hydrochloride significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine hydrochloride inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.

Cyclizine (1-10 mg/kg) hydrochloride enhances locomotor activity of mice in a dose-dependent manner.

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GPCR/G Protein

Neurokinin Receptor

Others

Others-Field

——

303-25-3

302.85

C18H22N2·HCl

>98% (HPLC)

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CN1CCN(CC1)C(c1ccccc1)c1ccccc1.Cl

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(-20℃)

With Ice Pack

≥ 2 years