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Demethyleneberberine
CAS No. 25459-91-0
Demethyleneberberine( —— )
Catalog No. M18314 CAS No. 25459-91-0
Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 147 | In Stock |
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| 5MG | 134 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 329 | In Stock |
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| 50MG | 477 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDemethyleneberberine
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NoteResearch use only, not for human use.
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Brief DescriptionDemethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.
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DescriptionDemethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either in vitro or in vivo.Demethyleneberberine suppresses CYP2E1, hypoxia inducible factor α, and inducible nitric oxide synthase, which contributes to oxidative stress and restored sirtuin 1/AMP-activated protein kinase/peroxisome proliferator-activated receptor-γ coactivator-1α pathway-associated fatty acid oxidation in chronic ethanol-fed mice.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorCYP17|HIF|NOS
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Research Area——
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Indication——
Chemical Information
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CAS Number25459-91-0
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Formula Weight324.35
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Molecular FormulaC19H18NO4+
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (30.83 mMul)
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SMILESOc1cc2c3cc4ccc(OC)c(OC)c4c[n+]3CCc2cc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang P1,et al.J Pharmacol Exp Ther. 2015 Jan;352(1):139-47.
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