Ginkgolide A( Ginkgolide A | BN 52020 | BN 52020 )

Catalog No. M18065 CAS No. 15291-75-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Ginkgolide A
Note

Research use only, not for human use.
Brief Description

Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Description

Ginkgolide A is GSK-3β inhibitor and potential PXR agonist found in Ginkgo. It decreases phosphorylation of Tau protein, prevents neointimal hyperplasia and decreases anxiety.
In Vitro

——
In Vivo

——
Synonyms

Ginkgolide A | BN 52020 | BN 52020
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

GABAR
Research Area

Inflammation/Immunology
Indication

——

CAS Number

15291-75-5
Formula Weight

408.4
Molecular Formula

C20H24O9
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL 244.86 mM
SMILES

O1[C@H]2C[C@]34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)[C@H](O)[C@]43[C@H](C(C)(C)C)C5)[C@@]2(O)[C@H](C)C1=O
Chemical Name

9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta(c)furo(2,3-b)furo(3',2':3,4)cyclopenta(1,2-d)furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-

1. Zhao Q, Gao C, Cui Z. Int Immunopharmacol. 2015 Apr;25(2):242-8.

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