Cart
sales@molnova.com
ID-8
CAS No. 147591-46-6
ID-8( ID-8 | ID 8 | ID8 )
Catalog No. M18041 CAS No. 147591-46-6
ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 5MG | 38 | In Stock |
|
| 10MG | 53 | In Stock |
|
| 25MG | 93 | In Stock |
|
| 50MG | 152 | In Stock |
|
| 100MG | 226 | In Stock |
|
| 200MG | 334 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameID-8
-
NoteResearch use only, not for human use.
-
Brief DescriptionID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
-
DescriptionID-8 is a DYRK inhibitor. ID-8 could support Wnt-induced human embryonic stem cell proliferation and survival without differentiation. Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) is the target of the small molecule ID-8. Its role in human pluripotent cell renewal was confirmed by DYRK knockdown in human embryonic stem cells.
-
In VitroID-8 (0.1-10 μM) increases human embryonic stem cell (hESC) survival.ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month.
-
In Vivo——
-
SynonymsID-8 | ID 8 | ID8
-
PathwayOthers
-
TargetOther Targets
-
RecptorDYRK
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number147591-46-6
-
Formula Weight298.29
-
Molecular FormulaC16H14N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 47 mg/mL; 157.56 mM
-
SMILESCOc1ccc(cc1)n1c(C)c(c2c1cc(O)cc2)[N+](=O)[O-]
-
Chemical Name1-(4-methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
5,7-Dichloroquinolin...
5,7-Dichloroquinoline
-
Pivagabine
Pivagabine is a derivative of hydrophobic 4-aminobutyric acid, with neuromodulatory activity. Pivagabine penetrates the blood-brain barrier in rats. Pivagabine antagonizes the effects of foot shock on both GABAA receptor function and corticotropin-releasing factor (CRF) concentrations in rat brain.
-
ATI-2341 TFA (133787...
ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).
