Isochlorogenic acid B( Isochlorogenic acid B )

Catalog No. M18029 CAS No. 14534-61-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Isochlorogenic acid B
Note

Research use only, not for human use.
Brief Description

Isochlorogenic acid B has antioxidant activity.
Description

Isochlorogenic acid B has antioxidant activity.
In Vitro

3,4-Dicaffeoylquinic acid acts as a greater primary antioxidant than its methanol extract, by having higher ferric reducing activity (EC50 2.18 μg/ml), β-carotene bleaching activity (EC50 23.85 μg/ml) and DPPH scavenging activity (EC50 68.91 μg/ml). 3,4-Dicaffeoylquinic acid exhibits a remarkable dose-dependent inhibitory effect on NCI-H23 (human lung adenocarcinoma) cell lines (EC50 3.26 μg/ml) and is found to be apoptotic in nature based on a clear indication of DNA fragmentation. 3,4-Dicaffeoylquinic acid also displays a concentration-dependent α-glucosidase inhibition with EC50 241.80 μg/ml.
In Vivo

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Synonyms

Isochlorogenic acid B
Pathway

Angiogenesis
Target

HIF/HIF Prolyl-hydroxylase
Recptor

Antioxidant
Research Area

Others-Field
Indication

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CAS Number

14534-61-3
Formula Weight

516.45
Molecular Formula

C25H24O12
Purity

>98% (HPLC)
Solubility

DMSO : 50 mg/mL 96.81 mM;
SMILES

C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)OC(=O)C=CC3=CC(=C(C=C3)O)O)O
Chemical Name

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