Cart
sales@molnova.com
UNC669
CAS No. 1314241-44-5
UNC669( —— )
Catalog No. M17941 CAS No. 1314241-44-5
UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 10MG | 29 | In Stock |
|
| 25MG | 45 | In Stock |
|
| 50MG | 62 | In Stock |
|
| 100MG | 111 | In Stock |
|
| 200MG | 163 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUNC669
-
NoteResearch use only, not for human use.
-
Brief DescriptionUNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
-
DescriptionUNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
-
In VitroL3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans.
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorL3MBTL1| L3MBTL3| L3MBTL4
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1314241-44-5
-
Formula Weight338.24
-
Molecular FormulaC15H20BrN3O
-
Purity>98% (HPLC)
-
SolubilityDMSO : 50 mg/mL 147.82 mM;
-
SMILESc1c(cncc1Br)C(=O)N1CCC(CC1)N1CCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.
molnova catalog
related products
-
CP-312
CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.
-
GSK4112
A potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assay.
-
Lys05
Lys05 (Lys01 trihydrochloride, PS-1001)?is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ); shows IC50 values of 3.6, 3.8, 6 and 7.9 uM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay.
