Dyngo-4a( Dyngo-49 | Dyngo 49 | Hydroxy Dynasore )

Catalog No. M17909 CAS No. 1256493-34-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Dyngo-4a
Note

Research use only, not for human use.
Brief Description

Dyngo-4a , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively.
Description

Dyngo-49 is a dynamin inhibitor.
In Vitro

——
In Vivo

Animal Model:CD-1 mice.Dosage:30 mg/kg Administration:Intraperitoneal injection; 1.5–2 h before BoNT/A injection Result:Protected BoNT/A-induced paralysis in vivo.
Synonyms

Dyngo-49 | Dyngo 49 | Hydroxy Dynasore
Pathway

Others
Target

Other Targets
Recptor

DynI (brain)| DynI (rec)| DynII (rec)
Research Area

Neurological Disease
Indication

——

CAS Number

1256493-34-1
Formula Weight

338.31
Molecular Formula

C18H14N2O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (147.79 mM)
SMILES

c1c(c(cc2ccccc12)O)C(=O)NN=Cc1c(cc(c(c1)O)O)O
Chemical Name

3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide

1. Harper CB., Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol. 2013 Feb;23(2):90-101.

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