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BMS-833923

CAS No. 1059734-66-5

BMS-833923( XL-139 )

Catalog No. M17789 CAS No. 1059734-66-5

BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	51	In Stock
5MG	44	In Stock
10MG	70	In Stock
25MG	123	In Stock
50MG	193	In Stock
100MG	350	In Stock
200MG	514	In Stock
500MG	817	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BMS-833923
Note

Research use only, not for human use.
Brief Description

BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
Description

BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
In Vitro

——
In Vivo

——
Synonyms

XL-139
Pathway

Apoptosis
Target

IL Receptor
Recptor

Smoothened
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

1059734-66-5
Formula Weight

473.57
Molecular Formula

C30H27N5O
Purity

>98% (HPLC)
Solubility

DMSO : 50 mg/mL 105.58 mM;
SMILES

c12c(c(nc(n1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1C)CNC)c1ccccc1)cccc2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Tang JY, et al. Semin Cutan Med Surg. 2011, 30(4 Suppl), S14-18.2. Zaidi AH, et al. Y Invest. 2013, 31(7), 480-489.

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