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Chlorphenesin
CAS No. 104-29-0
Chlorphenesin( Chlorphenesin | NSC 6401 | NSC6401 | NSC-6401 )
Catalog No. M17775 CAS No. 104-29-0
Chlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 50MG | 29 | In Stock |
|
| 100MG | 41 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 105 | In Stock |
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| 1G | 156 | In Stock |
|
Biological Information
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Product NameChlorphenesin
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NoteResearch use only, not for human use.
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Brief DescriptionChlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release.
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DescriptionChlorphenesin is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. It is also used as an antimycotic agent.(In Vitro):Chlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs).Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs.
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In VitroChlorphenesin (0.01, 0.1, 0.3%; 30-min exposure) significantly reduces the activity of the Akt pathway in a dose-dependent manner in human meibomian gland epithelial cells (HMGECs).Chlorphenesin (0.1, 0.3%; 24 hours) induces immortalized HMGECs (IHMGECs) rounding, atrophy, poor adherence, detachme and significantly reduces the number of IHMGECs.
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In Vivo——
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SynonymsChlorphenesin | NSC 6401 | NSC6401 | NSC-6401
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PathwayApoptosis
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TargetNF-κB
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RecptorHistamine relase
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Research Area——
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Indication——
Chemical Information
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CAS Number104-29-0
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Formula Weight202.63
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Molecular FormulaC9H11ClO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (493.51 mM)
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SMILESOCC(O)COc1ccc(Cl)cc1
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Chemical Name1,2-Propanediol, 3-(4-chlorophenoxy)- (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Collman J P, et al. ChemInform Abstract: A SILICA-SUPPORTED RHODIUM HYDROFORMYLATION CATALYST: EVIDENCE FOR DINUCLEAR ELIMINATION[J]. 1983, 105(12):7288-7294.
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