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Vamorolone
CAS No. 13209-41-1
Vamorolone( VBP15 )
Catalog No. M23477 CAS No. 13209-41-1
Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
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| 2MG | 42 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 291 | In Stock |
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| 100MG | 435 | In Stock |
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| 200MG | 626 | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVamorolone
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NoteResearch use only, not for human use.
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Brief DescriptionVamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.
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DescriptionVamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition and substantially decreases hormonal effects.
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In Vitro——
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In VivoAnimal Model:C57BL/6 mice (experimental autoimmune encephalomyelitis)Dosage:30 mg/kg Administration:Orally; daily for 20 days (starting one day prior to MOG 33-55 peptide immunization and continuing)Result:Reduced CNS inflammation in murine experimental autoimmune encephalomyelitis.
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SynonymsVBP15
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PathwayApoptosis
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TargetNF-κB
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RecptorGlucocorticoid Receptor|Mineralocorticoid Receptor|NF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number13209-41-1
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Formula Weight356.46
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Molecular FormulaC22H28O4
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Purity>98% (HPLC)
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SolubilityDMSO:62.5 mg/mL (175.34 mM; Need ultrasonic)
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SMILESC[C@H](C[C@@H]([C@@H]1CC2)[C@]3(C)CC=C1[C@@](C)(C=C1)C2=CC1=O)[C@@]3(C(CO)=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Heier CR, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. EMBO Mol Med. 2013 Oct;5(10):1569-85.
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